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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Integrin alpha-V/beta-5
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126594
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
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Affinity Data
Ki: 6nM
Assay Description:
Binding affinity for alphaV-beta3 vitronectin receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126596
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12nM
Assay Description:
Binding affinity for alphav/beta 3 vitronectin receptor in HEK cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126594
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 32nM
Assay Description:
Binding affinity for alphaV-beta5 vitronectin receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126598
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 170nM
Assay Description:
Binding affinity for alphaV-beta3 vitronectin receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-IIb/beta-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126594
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity for alphav/beta 3 vitronectin receptor in HEK cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126594
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8nM
Assay Description:
Inhibition of human intergrin alphavbeta3 receptor by solid phase receptor assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-5
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126594
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Inhibition of integrin alphavbeta5 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126594
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
Assay Description:
Inhibition of human intergrin alphavbeta3 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50126594
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 96nM
Assay Description:
Inhibition of integrin alphavbeta1 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126596
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 470nM
Assay Description:
Binding affinity for alphaV-beta3 vitronectin receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-3
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50126594
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 500nM
Assay Description:
Inhibition of HEK 293 cell adhesion to vitronectin by human alphaV-beta3 integrin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-V/beta-6
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50126594
(3-Phenyl-4-{4-[3-(pyridin-2-ylamino)-propoxy]-phen...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.98E+4nM
Assay Description:
Inhibition of integrin alphabeta6 receptor expressed in HT29 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI