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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetDNA gyrase subunit B(Staphylococcus aureus)
Birla Institute of Technology

LigandPNGBDBM166646(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
Affinity DataIC50:  3.12E+3nMpH: 7.6 T: 2°CAssay Description:Supercoiling assay was performed using the commercially available kit (DNA gyrase supercoiling assay kit: SAS4001) from Inspiralis Pvt.limited, Norwi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Birla Institute Of Technology & Science-Pilani

Curated by ChEMBL
LigandPNGBDBM166646(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
Affinity DataIC50:  3.13E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase-mediated supercoiling of relaxed DNA using pBR 322 as substrate by agarose gel electrophoresis analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM166646(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Birla Institute of Technology

LigandPNGBDBM166646(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase B ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit B(Staphylococcus aureus)
Birla Institute of Technology

LigandPNGBDBM166646(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
Affinity DataIC50:  1.29E+4nMpH: 7.5Assay Description:Initially, equimolar quantities of about 0.5µM each of E. coli gyraseA and S. aureus gyraseB were incubated for a period of 45 min with salmon sperm ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed