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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
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Target
DNA gyrase subunit B
(Staphylococcus aureus)
Birla Institute of Technology
Ligand
BDBM166646
(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
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Affinity Data
IC50: 3.12E+3nM
pH: 7.6 T: 2°C
Assay Description:
Supercoiling assay was performed using the commercially available kit (DNA gyrase supercoiling assay kit: SAS4001) from Inspiralis Pvt.limited, Norwi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
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Target
DNA gyrase subunit A/B
(Staphylococcus aureus)
Birla Institute Of Technology & Science-Pilani
Curated by
ChEMBL
Ligand
BDBM166646
(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
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Affinity Data
IC50: 3.13E+3nM
Assay Description:
Inhibition of Staphylococcus aureus DNA gyrase-mediated supercoiling of relaxed DNA using pBR 322 as substrate by agarose gel electrophoresis analysi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Platelet-derived growth factor receptor alpha/beta
(Mus musculus (mouse))
TBA
Ligand
BDBM166646
(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
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Affinity Data
IC50: 1.29E+4nM
Assay Description:
Inhibition of Staphylococcus aureus DNA gyrase
More data for this Ligand-Target Pair
Target Info
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
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PC cid
PC sid
Similars
In Depth
Details
PubMed
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Target
DNA gyrase subunit B
(Staphylococcus aureus)
Birla Institute of Technology
Ligand
BDBM166646
(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
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Affinity Data
IC50: 1.29E+4nM
Assay Description:
Inhibition of Staphylococcus aureus DNA gyrase B ATPase activity
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
DNA gyrase subunit B
(Staphylococcus aureus)
Birla Institute of Technology
Ligand
BDBM166646
(4-((4-(furan-2-carboxamido)phenyl)amino)-4-oxobuta...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.29E+4nM
pH: 7.5
Assay Description:
Initially, equimolar quantities of about 0.5µM each of E. coli gyraseA and S. aureus gyraseB were incubated for a period of 45 min with salmon sperm ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI