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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM210750
(US9290454, 3.2)
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Affinity Data
Ki: 1.30nM
Assay Description:
Antagonist activity at CRTh2 (unknown origin) assessed as inhibition of CD11b activation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM210750
(US9290454, 3.2)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.5nM
Assay Description:
Antagonist activity at human CRTh2 expressed in HEK cells assessed as inhibition of DK-PGD2-mediated attenuation of forskolin-induced cAMP accumulati...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prostaglandin D2 receptor 2
(Homo sapiens (Human))
Merck
Curated by
ChEMBL
Ligand
BDBM210750
(US9290454, 3.2)
Copy SMILES
Copy InChI
Affinity Data
Ki: 6.50nM ΔG°: -50.6kJ/mole
pH: 7.4 T: 2°C
Assay Description:
Radioligand binding was performed using filtration or scintillation proximity assay (SPA) technology. SPA assays were done at room temperature in 10 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI