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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356646(CHEMBL1917389)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356646(CHEMBL1917389)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356646(CHEMBL1917389)
Affinity DataIC50:  29nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation counting in the presence of 0.1% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356646(CHEMBL1917389)
Affinity DataIC50:  104nMAssay Description:Antagonist activity human CRTH2 expressed in chinese hamster CHO cells assessed as inhibition of PGD2-induced [35S]GTPgamma binding by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356646(CHEMBL1917389)
Affinity DataIC50:  114nMAssay Description:Antagonist activity at human CRTH2 expressed in human CHO cells by cellular dielectric spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356646(CHEMBL1917389)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at human CRTH2 expressed in human CHO cells by cellular dielectric spectroscopy in the presence of PGD2 and 0.1% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356646(CHEMBL1917389)
Affinity DataIC50:  1.44E+3nMAssay Description:Inhibition of human recombinant CYP2C9 expressed in baculovirus infected insect cells preincubated for 15 mins measured after 30 mins by luminescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356646(CHEMBL1917389)
Affinity DataIC50:  6.90E+3nMAssay Description:Antagonist activity at CRTH2 in human blood cells assessed as inhibition of PGD2-induced eosinophil cell shape change after 10 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed