Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Gilead Sciences

LigandBDBM33417(pyrimidinol carboxylic acid, 9)Copy SMILESCopy InChI

Affinity DataIC50:  1.45E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar

Ligand InfoMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetRibonuclease H1(Homo sapiens (Human))
Gilead Sciences

LigandBDBM33417(pyrimidinol carboxylic acid, 9)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI