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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetBeta-galactosidase(Bos taurus (Bovine))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataIC50:  460nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-galactosidase(Bos taurus (Bovine))
Savitribai Phule Pune University (Formerly University Of Pune)

Curated by ChEMBL
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of bovine liver beta-galactosidase using 10 mM p-nitrophenyl-beta-D-galactopyranoside as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
UniversitÉ

US Patent
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))
Affinity DataIC50:  3.87E+5nMAssay Description:The inhibiting activity on recombinant human acid α-glucosidase (rhGAA) of the compounds is implemented using the Fluopol-ABPP method (Fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent