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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Beta-galactosidase
(Bos taurus (Bovine))
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 1.50E+3nM
Assay Description:
Tested for competitive inhibition of bovine liver beta-galactosidase
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Lactase/phlorizin hydrolase
(Rattus norvegicus)
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 1.90E+3nM
Assay Description:
Tested for competitive inhibition of rat intestinal lactase
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Beta-galactosidase
(Bos taurus (Bovine))
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 3.00E+3nM
Assay Description:
Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometry
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-galactosidase
(Bos taurus (Bovine))
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Copy InChI
Affinity Data
IC50: 3.10E+3nM
Assay Description:
Concentration that causes 50% inhibition of mammalian cytosolic beta-galactosidase was determined in bovine liver
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-galactosidase
(Rattus norvegicus)
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 4.00E+3nM
Assay Description:
Concentration that causes 50% inhibition of mammalian lactase beta-galactosidase was determined in rat intestine
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lactase/phlorizin hydrolase
(Rattus norvegicus)
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Copy InChI
Affinity Data
IC50: 4.30E+3nM
Assay Description:
Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometry
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Lysosomal acid glucosylceramidase
(Bos taurus)
University Of Toyama
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 5.60E+3nM
Assay Description:
Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sucrase-isomaltase, intestinal
(Rattus norvegicus (Rat))
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 6.00E+3nM
Assay Description:
Inhibition of Wistar rat intestinal isomaltase by glucose B-test
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Neutral alpha-glucosidase C
(Mus musculus)
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 6.40E+3nM
Assay Description:
Concentration that causes 50% inhibition of mammalian alpha-glucosidase (isomaltase) was determined in rat intestine
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Ceramide glucosyltransferase
(Mus musculus)
TBA
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
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PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Beta-glucosidase A
(Caldocellum saccharolyticum)
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 1.00E+5nM
Assay Description:
Concentration that causes 50% inhibition of mammalian cellobiase beta-glucosidase was determined in rat intestine
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Lysosomal alpha-glucosidase
(Rattus norvegicus)
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 5.00E+5nM
Assay Description:
Concentration that causes 50% inhibition of mammalian alpha-glucosidase (maltase) was determined in rat intestine
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Non-lysosomal glucosylceramidase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysis
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Tissue alpha-L-fucosidase
(Homo sapiens (Human))
Hokuriku University
Curated by
ChEMBL
Ligand
BDBM50292389
(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
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Affinity Data
IC50: 1.00E+6nM
Assay Description:
Concentration that causes 50% inhibition of mammalian alpha-L-fucosidase was determined in bovine epididymis
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI