Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289705(CHEMBL3745884)
Affinity DataEC50:  2.82E+3nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289705(CHEMBL3745884)
Affinity DataEC50:  2.80E+3nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50289705(CHEMBL3745884)
Affinity DataEC50:  400nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in human A549 cells incubated for 25 mins by YFP-based fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed