Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 24 hits in this display
BDBM108215(5-(hydroxymethyl)-5H,6H,7H,8H-imidazo[1,2- a]pyrid...)
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 400nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3965 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 1.00E+3nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3130 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
Beta-mannosidase(Bacteroides thetaiotaomicron)The Medical School, Newcastle University
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 4.30E+4nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3994 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 4.60E+4nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3991 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 7.00E+4nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2948 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 9.00E+4nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 2199 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 9.60E+4nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3990 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 2.60E+5nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3858 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 2.70E+5nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3962 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 3.60E+5nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 4073 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 6.00E+5nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 1032 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 7.90E+5nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3963 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 8.60E+5nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 4093 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 1.60E+6nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 4092 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 1.80E+6nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 1878 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM36373((5R,6R,7S,8R)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)...)
Ki: 5.80E+6nMAssay Description:Inhibition of Bacteroides thetaiotaomicron GH92 alpha-mannosidase 3784 assessed as reduction of mannose release using 4NP-mannopyranoside substrateMore data for this Ligand-Target Pair
BDBM108215(5-(hydroxymethyl)-5H,6H,7H,8H-imidazo[1,2- a]pyrid...)
BDBM108215(5-(hydroxymethyl)-5H,6H,7H,8H-imidazo[1,2- a]pyrid...)
IC50: 91.6nMpH: 5.2Assay Description:The assays were performed at 37°C with 4-MU-β-ᴅ-Glu as the substrate in Mcllvaine buffer (sodium citrate (100mM) and sodium phosphate...More data for this Ligand-Target Pair
BDBM108215(5-(hydroxymethyl)-5H,6H,7H,8H-imidazo[1,2- a]pyrid...)
BDBM108215(5-(hydroxymethyl)-5H,6H,7H,8H-imidazo[1,2- a]pyrid...)
IC50: 230nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
BDBM108215(5-(hydroxymethyl)-5H,6H,7H,8H-imidazo[1,2- a]pyrid...)
IC50: 7.29E+3nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair
BDBM108215(5-(hydroxymethyl)-5H,6H,7H,8H-imidazo[1,2- a]pyrid...)
IC50: 9.85E+4nMpH: 10.6 T: 2°CAssay Description:In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min....More data for this Ligand-Target Pair