Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL

LigandBDBM50356656(CHEMBL1917399)Copy SMILESCopy InChI

Affinity DataKi:  28nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

Curated by ChEMBL

LigandBDBM50356656(CHEMBL1917399)Copy SMILESCopy InChI

Affinity DataIC50:  680nMAssay Description:Antagonist activity at CRTH2 in human blood cells assessed as inhibition of PGD2-induced eosinophil cell shape change after 10 mins by flow cytometryMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI