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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Methionine aminopeptidase 2
(Homo sapiens (Human))
Northern Illinois University
Curated by
ChEMBL
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: 55nM
Assay Description:
Inhibition of recombinant full length human N-terminal GST/His6-tagged methionine aminopeptidase 2 expressed in baculovirus infected sf9 cells using ...
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Target Info
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KEGG
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B.MOAD
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3D Structure (crystal)
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Target
Methionine aminopeptidase 2
(Homo sapiens (Human))
Northern Illinois University
Curated by
ChEMBL
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: 1.27E+3nM
Assay Description:
Inhibition of human methionine aminopeptidase 2
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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3D Structure (crystal)
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Target
Botulinum neurotoxin type A
(Clostridium botulinum)
U.S. Army Medical Research Institute Of Infectious Diseases
Curated by
ChEMBL
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: 1.90E+3nM
Assay Description:
Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...
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Target Info
PDB
MMDB
NCI pathway
Reactome pathway
UniProtKB/SwissProt
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Target
Bromodomain-containing protein 4
(Homo sapiens (Human))
TBA
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: 6.47E+3nM
Assay Description:
Inhibition of BRD4 (unknown origin)
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Target
Methionine aminopeptidase 1
(Homo sapiens (Human))
Northern Illinois University
Curated by
ChEMBL
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: 1.29E+4nM
Assay Description:
Inhibition of human methionine aminopeptidase 1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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antibodypedia
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Target
Methionine aminopeptidase 1
(Homo sapiens (Human))
Northern Illinois University
Curated by
ChEMBL
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: >1.50E+4nM
Assay Description:
Inhibition of recombinant full length human His-tagged methionine aminopeptidase 1 expressed in Escherichia coli BL21(DE3) using methionylprolyl-p-ni...
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Target Info
PDB
MMDB
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Target
Integrase
(Human immunodeficiency virus 1)
University Of Southern California
Curated by
ChEMBL
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of HIV-1 integrase strand transfer activity
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Target
Integrase
(Human immunodeficiency virus 1)
University Of Southern California
Curated by
ChEMBL
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of HIV-1 integrase 3'-processing activity
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Target
Beta-galactosidase
(Escherichia coli)
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: >6.66E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, C...
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Target
C-C chemokine receptor type 6
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: >6.66E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...
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Target
Bile salt export pump
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
IC50: 3.57E+5nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
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Target Info
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Target
Vacuolar aminopeptidase 1
(Saccharomyces cerevisiae)
Nmmlsc
Curated by
PubChem BioAssay
Ligand
BDBM76305
(5-chloranylquinolin-8-ol | 5-chloro-8-quinolinol |...)
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Affinity Data
EC50: 2.08E+5nM
Assay Description:
University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...
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Target Info
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PC cid
PC sid
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