Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 33 hits in this display
Collagenase 3(Homo sapiens (Human))The Research Foundation of State University of New York
US Patent
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
Collagenase 3(Homo sapiens (Human))The Research Foundation of State University of New York
US Patent
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
Collagenase 3(Homo sapiens (Human))The Research Foundation of State University of New York
US Patent
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
IC50: 9.00E+3nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
IC50: 9.00E+3nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
IC50: 1.00E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
IC50: 2.25E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
IC50: 2.25E+4nMAssay Description:Table 1 shows the IC50 of curcumin, compound 1, and compound 2, compared to a standard Zn++ binding & MMPI (matrix metalloproteinase inhibitor), 1,10...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
IC50: 3.50E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
VIM-13(Pseudomonas aeruginosa)Hospital Son Dureta
Curated by ChEMBL
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
IC50: 7.00E+4nMT: 2°CAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
IC50: 7.00E+4nMAssay Description:Table 10: The efficacy of MMP-2 inhibition was as follows: compound 6>compound 7>compound 8. Although compound 6 showed similar efficacy as curcumin ...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
IC50: 7.00E+4nMAssay Description:It has been observed that 50 and 100 μM concentrations of curcumin decreased TNFα production by endotoxin-stimulated human monocytes (HMs) ...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
Thermolysin(Bacillus thermoproteolyticus)Osaka Organic Chemical Industry
Curated by ChEMBL
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
EC50: 5.90E+3nMAssay Description:Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
EC50: 3.98E+3nMAssay Description:Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysisMore data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
EC50: 4.90E+3nMAssay Description:Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun...More data for this Ligand-Target Pair
BDBM50092158(1,10-phenanthroline | CHEMBL415879 | US10669227, C...)
EC50: 3.90E+3nMAssay Description:Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysisMore data for this Ligand-Target Pair