Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 99 hits in this display
BDBM50330742(2-(2-Chlorophenyl)-5-[(1-methyl-1H-pyrazol-3-yl)me...)Ki: 47nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330740(2-(2-chlorophenyl)-4-((4-(3-methoxyphenyl)piperazi...)Ki: 65nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 72nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 76nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
BDBM50330744(4-((2-chlorobenzyloxy)methyl)-2-(2-chlorophenyl)-5...)Ki: 82nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 87nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 93nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 94nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
BDBM50330743(4-(benzyloxymethyl)-2-(2-chlorophenyl)-5-(pyrazin-...)Ki: 95nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 101nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 103nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 103nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 111nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 111nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 112nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
BDBM50330738(2-(2-chloro-4-fluorophenyl)-5-(2-(pyridin-2-yl)eth...)Ki: 114nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330745(2-(2-chlorophenyl)-4-((4-fluorophenoxy)methyl)-5-m...)Ki: 114nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 116nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
BDBM50330746(2-(2-chlorophenyl)-4-(2-fluorophenyl)-5-methyl-1H-...)Ki: 128nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 131nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 142nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
Ki: 144nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
BDBM50330739(2-(2-chlorophenyl)-4-((methyl(phenyl)amino)methyl)...)Ki: 151nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330737(4-((4-fluorophenoxy)methyl)-5-(2-methoxyethyl)-2-(...)Ki: 153nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 156nMAssay Description:Antagonist activity at human NOX4 expressed in CHO cell membrane coexpressing tetracylin repressor assessed as inhibition of ROS production after 20 ...More data for this Ligand-Target Pair
BDBM50330718(2-(2-chlorophenyl)-4-methyl-5-(3-phenylprop-2-ynyl...)Ki: 158nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330736(4-((benzyl(methyl)amino)methyl)-2-(2-chloro-4-fluo...)Ki: 165nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330722(2-(2-chlorophenyl)-4-methyl-5-(pyridin-2-ylmethyl)...)Ki: 165nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330741(2-(2-chlorophenyl)-4-((methyl(phenyl)amino)methyl)...)Ki: 172nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330734(4-Methyl-2-(2-methylphenyl)-5-(pyridine-2-ylmethyl...)Ki: 173nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330709(2-(2-chloro-4-fluorophenyl)-4,5-dimethyl-1H-pyrazo...)Ki: 213nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330704(2-(2-chlorophenyl)-4,5-dimethyl-1H-pyrazolo[4,3-c]...)Ki: 215nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330719(CHEMBL1276857 | N-(2-(2-chlorophenyl)-4-methyl-3,6...)Ki: 218nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330729(2-(2,5-dichlorobenzyl)-4-methyl-5-(pyridin-2-ylmet...)Ki: 218nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330733(2-(2-chloro-4-fluorophenyl)-4-methyl-5-(pyridin-2-...)Ki: 235nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330716(2-(2-chlorophenyl)-5-(2-(dimethylamino)ethyl)-4-me...)Ki: 235nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330723(2-(2-chlorophenyl)-4-methyl-5-((6-morpholinopyridi...)Ki: 236nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330703(1-acetyl-2-(2-chlorophenyl)-4-methyl-5-(pyridin-3-...)Ki: 240nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330721(4-((2-(2-chlorophenyl)-4-methyl-3,6-dioxo-2,3-dihy...)Ki: 259nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330732(2-(4-chlorobenzyl)-4-methyl-5-(pyridin-2-ylmethyl)...)Ki: 259nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330701(1-(2-(3-methoxyphenyl)acetyl)-4-methyl-2-phenyl-5-...)Ki: 285nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330711(3-(4,5-dimethyl-3,6-dioxo-5,6-dihydro-1H-pyrazolo[...)Ki: 293nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330705(2-(2-fluorophenyl)-4,5-dimethyl-1H-pyrazolo[4,3-c]...)Ki: 308nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330725(2-(2-methoxyethyl)-4-methyl-5-(pyridin-2-ylmethyl)...)Ki: 313nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330728(2-(2-(4-chlorophenoxy)ethyl)-4-methyl-5-(pyridin-2...)Ki: 326nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330713(CHEMBL1275631 | N-(3-(4,5-dimethyl-3,6-dioxo-5,6-d...)Ki: 328nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330727(4-methyl-2-phenethyl-5-(pyridin-2-ylmethyl)-1H-pyr...)Ki: 334nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330712(2-(3-chlorophenyl)-4,5-dimethyl-1H-pyrazolo[4,3-c]...)Ki: 340nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330731(2-(2-chloro-4-fluorobenzyl)-4-methyl-5-(pyridin-2-...)Ki: 342nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330688(4-methyl-2-phenyl-5-(pyridin-3-ylmethyl)-1H-pyrazo...)Ki: 373nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330724(2,4-dimethyl-5-(pyridin-2-ylmethyl)-1H-pyrazolo[4,...)Ki: 387nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330702(1-acetyl-4-methyl-5-(pyridin-3-ylmethyl)-2-o-tolyl...)Ki: 398nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330694(1-acetyl-4-methyl-2-phenyl-5-(pyridin-3-ylmethyl)-...)Ki: 409nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330717(2-(2-chlorophenyl)-4-methyl-5-(4-(4-methylpiperazi...)Ki: 428nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330726(4-methyl-2-(2-morpholinoethyl)-5-(pyridin-2-ylmeth...)Ki: 445nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330735(2-(7-chloroquinolin-4-yl)-4-methyl-5-(pyridin-2-yl...)Ki: 458nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330730(2-benzyl-4-methyl-5-(pyridin-2-ylmethyl)-1H-pyrazo...)Ki: 463nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330720(2-(2-chlorophenyl)-4-methyl-5-(4-((4-methylpiperaz...)Ki: 515nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330714(2-(2-chlorophenyl)-5-(cyclohexylmethyl)-4-methyl-1...)Ki: 520nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330715(2-(2-chlorophenyl)-5-(3-hydroxypropyl)-4-methyl-1H...)Ki: 565nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 840nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
BDBM50330692(5-benzyl-2-(4-fluorophenyl)-4-methyl-1H-pyrazolo[4...)Ki: 878nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 880nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
BDBM50330691(2-(benzo[d]thiazol-2-yl)-4-methyl-5-morpholino-1H-...)Ki: 1.21E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330707(4,5-dimethyl-2-(5-(4-methylpiperazin-1-ylsulfonyl)...)Ki: 1.42E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330685(5-(2-(1H-indol-3-yl)ethyl)-2-(benzo[d]thiazol-2-yl...)Ki: 1.85E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330706(4,5-dimethyl-2-(4-phenylthiazol-2-yl)-1H-pyrazolo[...)Ki: 1.95E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330708(2,4,5-trimethyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,...)Ki: 2.18E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 2.33E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 2.36E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 2.39E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 2.63E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
BDBM50330710(2-(4-(benzyloxy)phenyl)-4,5-dimethyl-1H-pyrazolo[4...)Ki: 3.06E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 3.12E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
BDBM50330687(4-((2-(benzo[d]thiazol-2-yl)-4-methyl-3,6-dioxo-2,...)Ki: 4.22E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330684(5-(2-(1H-imidazol-4-yl)ethyl)-2-(benzo[d]thiazol-2...)Ki: 4.73E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330689(4-methyl-5-phenethyl-2-phenyl-1H-pyrazolo[4,3-c]py...)Ki: 5.23E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330690(5-(benzo[d][1,3]dioxol-5-ylmethyl)-4-methyl-2-phen...)Ki: 5.44E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 6.35E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 6.83E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 9.31E+3nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
BDBM50330686(5-(furan-2-ylmethyl)-4-methyl-2-phenyl-1H-pyrazolo...)Ki: 9.49E+3nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 1.31E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 2.40E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 2.64E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 2.70E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 2.77E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
BDBM50330695(2-(benzo[d]thiazol-2-yl)-1-benzyl-4-methyl-5-((tet...)Ki: >3.00E+4nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330700(1-(2-chlorobenzyl)-4-methyl-5-(3-(2-oxopyrrolidin-...)Ki: >3.00E+4nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330699(5-(2-(1H-indol-3-yl)ethyl)-1-(4-fluorobenzyl)-4-me...)Ki: >3.00E+4nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330696(2-(benzo[d]thiazol-2-yl)-1-(2-chlorobenzyl)-4-meth...)Ki: >3.00E+4nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330697(2-(benzo[d]thiazol-2-yl)-4-methyl-1-(pyridin-2-ylm...)Ki: >3.00E+4nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330698(2-(2-chlorophenyl)-5-(3-ethoxypropyl)-4-methyl-1-(...)Ki: >3.00E+4nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
BDBM50330693(2-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)-4-methyl-...)Ki: >3.00E+4nMAssay Description:Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPHMore data for this Ligand-Target Pair
Ki: 3.38E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 3.46E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 3.56E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair
Ki: 3.76E+4nMAssay Description:Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assayMore data for this Ligand-Target Pair