Affinity DataIC50: 0.0200nMAssay Description:Antibacterial activity against Streptococcus faecalis assessed as growth inhibitionMore data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 5nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antimicrobial activity against Enterococcus faecalis ATCC 29212 assessed as microbial growth inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 17nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 24nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Affinity DataIC50: 28.6nMAssay Description:Antibacterial activity against Streptococcus faecalis by broth microdilution techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 36.2nMAssay Description:Antibacterial activity against Enterococcus faecalis MTCC 439 incubated overnight by broth dilution techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 41.4nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 49nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 51nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 29212 incubated for 16 hrs by broth microdilution methodMore data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 58nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 73nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 130nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 130nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Affinity DataIC50: 167nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 51299 assessed as growth inhibition using fresh sample in DMSO by CLSI methodMore data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 200nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Affinity DataIC50: 219nMAssay Description:Concentration (IC50) to inhibit the growth of Streptococcus faecalis.More data for this Ligand-Target Pair
Affinity DataIC50: 401nMAssay Description:Concentration (IC50) to inhibit the growth of Streptococcus faecalis.More data for this Ligand-Target Pair
Affinity DataIC50: 445nMAssay Description:Antibacterial activity against Streptococcus faecalis by broth microdilution techniqueMore data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 450nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Antibacterial activity against Enterococcus faecalis incubated for 16 to 24 hrs by broth microdilution based spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 603nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 51299 assessed as growth inhibition using fresh sample in DMSO by CLSI methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 29212 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of P450 sccMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Antibacterial activity against vancomycin-sensitive Enterococcus faecalis 12-5 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of cholesterol side chain cleavage cytochrome P450More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 1.30E+3nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 1.40E+3nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth dilution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)
US Patent
Cortendo AB (PUBL)
US Patent
Affinity DataIC50: 1.80E+3nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth dilution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.23E+3nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.27E+3nMAssay Description:Antibacterial activity against low level vancomycin-resistant Enterococcus faecalis ATCC 51299 by plate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.29E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.34E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 51299 assessed as growth inhibition using fresh sample in DMSO by CLSI methodMore data for this Ligand-Target Pair