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Found 18 Enz. Inhib. hit(s) with Target = 'DNA oxidative demethylase ALKBH2'
TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM32021(4,5-bis(oxidanyl)-9,10-bis(oxidanylidene)anthracen...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of human ALKBH2 by HPLC analysisMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416766(CHEMBL5285500)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human full lenth N-terminal His6-tagged ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50592071(CHEMBL5169684)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416765(CHEMBL5269140)
Affinity DataIC50:  2.58E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50596053(CHEMBL5173876)
Affinity DataIC50:  2.59E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) cells using 15-mer m1A-ssDNA as substrate incubated for 10 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416762(CHEMBL5288180)
Affinity DataIC50:  4.27E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416836(CHEMBL5288308)
Affinity DataIC50:  4.62E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416763(CHEMBL5282569)
Affinity DataIC50:  5.64E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416764(CHEMBL5266761)
Affinity DataIC50:  5.66E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416761(CHEMBL5286685)
Affinity DataIC50:  6.52E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416767(CHEMBL5276266)
Affinity DataIC50:  8.53E+4nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ALKBH2 demethylase activity by restriction endonuclease digestion assayMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416768(CHEMBL5283651)
Affinity DataIC50:  1.07E+5nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cellsMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM26106(CHEMBL90852 | N-oxalyl glycine, 1a | NOG | Oxalylg...)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) cells using 15-mer m1A-ssDNA as substrate incubated for 10 m...More data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50344962((2S)-2-HYDROXYPENTANEDIOIC ACID | CHEMBL1615211 | ...)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of N-terminal His-tagged human full length ALKBH2 expressed in Escherichia coliMore data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50416550(CHEMBL5274121)
Affinity DataIC50:  1.52E+5nMAssay Description:Inhibition of human ALKBH2 (56 to 258 residues) expressed in Escherichia coli BL21 (DE3) cells using 15-mer m1A-ssDNA as substrate incubated for 10 m...More data for this Ligand-Target Pair
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TargetDNA oxidative demethylase ALKBH2(Homo sapiens)TBA
LigandPNGBDBM50361471(CHEMBL1614745)
Affinity DataIC50:  4.24E+5nMAssay Description:Inhibition of N-terminal His-tagged human full length ALKBH2 expressed in Escherichia coliMore data for this Ligand-Target Pair
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