Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 136109
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM136109(US8853203, 123c | US9650377, Example 123c)
Affinity DataIC50:  8nMAssay Description:Activity of compounds of the present invention with respect to mGluR1 antagonism was examined by an assay based on measurements of L-glutamate induce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM136109(US8853203, 123c | US9650377, Example 123c)
Affinity DataIC50:  8nMAssay Description:Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM136109(US8853203, 123c | US9650377, Example 123c)
Affinity DataIC50:  226nMAssay Description:Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM136109(US8853203, 123c | US9650377, Example 123c)
Affinity DataIC50:  226nMAssay Description:Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...More data for this Ligand-Target Pair
In DepthDetails US Patent