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Found 5 of ic50 for monomerid = 50104351
TargetGlucagon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50104351(4-[5-(4-Fluoro-phenyl)-2-(4-methoxy-phenyl)-3H-imi...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104351(4-[5-(4-Fluoro-phenyl)-2-(4-methoxy-phenyl)-3H-imi...)
Affinity DataIC50:  100nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50104351(4-[5-(4-Fluoro-phenyl)-2-(4-methoxy-phenyl)-3H-imi...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against interleukin-1(IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50104351(4-[5-(4-Fluoro-phenyl)-2-(4-methoxy-phenyl)-3H-imi...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase enzyme from RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlucagon receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50104351(4-[5-(4-Fluoro-phenyl)-2-(4-methoxy-phenyl)-3H-imi...)
Affinity DataIC50:  1.30E+4nMAssay Description:Binding affinity towards human glucagon receptor in absence of Mg2+ expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed