Compile Data Set for Download or QSAR
maximum 50k data
Found 12 of ic50 for monomerid = 50190746
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  10.2nMAssay Description:Inhibition of rabbit NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Oryctolagus cuniculus (rabbit))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  10.2nMAssay Description:Inhibition of rabbit NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  14.3nMAssay Description:Inhibition of rat NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  14.3nMAssay Description:Inhibition of rat NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  18.9nMpH: 7.0Assay Description:Inhibition of human kidney NEP at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  18.9nMAssay Description:Inhibition of human NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  19.7nMAssay Description:Inhibition of human recombinant NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  19.7nMAssay Description:Inhibition of human recombinant NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  26nMAssay Description:Inhibition of dog NEPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50:  31.8nMpH: 7.4Assay Description:Inhibition of human kidney NEP at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of dog ACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-converting enzyme 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50190746((R)-2-((1-((5-ethyl-1,3,4-thiadiazol-2-yl)carbamoy...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human ECE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed