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Found 3 of ic50 for monomerid = 50572117
TargetGTPase KRas(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50572117(CHEMBL4863593 | US20240043448, Example 91)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of biotinylated KRAS G12C/C51S/C80L/C118S mutant (unknown origin) pretreated for 60 mins followed by recombinant SOS addition by SOS-catal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGTPase KRas [2-169,G12C,C51S,C80L,C118S](Human sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50572117(CHEMBL4863593 | US20240043448, Example 91)
Affinity DataIC50:  1.40nMAssay Description:Each test compound (10 mM stock in DMSO) is diluted in DMSO to make a 10-point, 3-fold dilution series in a 384-well low dead volume microplate (Labc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGTPase KRas [2-169,G12C,C51S,C80L,C118S](Human sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50572117(CHEMBL4863593 | US20240043448, Example 91)
Affinity DataIC50:  113nMAssay Description:Each test compound (10 mM stock in DMSO) is diluted in DMSO to make a 10-point, 3-fold dilution series in a 384-well low dead volume microplate (Labc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent