TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Hunan Provinc
Curated by ChEMBL
Hunan Provinc
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Inhibition of FITC-BAK binding to His6 tagged MBP fused recombinant human MCL1 (172 to 327 residues) expressed in Escherichia coli by fluorescence po...More data for this Ligand-Target Pair
TargetBcl-2 homologous antagonist/killer(Homo sapiens)
National University Of Ireland Galway
Curated by ChEMBL
National University Of Ireland Galway
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Binding affinity to Mcl-1/Bak (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Hunan Provinc
Curated by ChEMBL
Hunan Provinc
Curated by ChEMBL
Affinity DataKi: 120nMAssay Description:Inhibition of FITC-labelled BAK BH3 peptide to MCL-1 (172 to 327 residues) (unknown origin) assessed as inhibition constant by fluorescence polarizat...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Hunan Provinc
Curated by ChEMBL
Hunan Provinc
Curated by ChEMBL
Affinity DataKi: 286nMAssay Description:Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo...More data for this Ligand-Target Pair
Affinity DataKi: 5.01E+3nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair