Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 11469
TargetRho-associated protein kinase 2(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM25472(CHEMBL519123 | N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-d...)
Affinity DataIC50:  1.5nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  10nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  10nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM7497(1-Azakenpaullone | 14-bromo-3,8,18-triazatetracycl...)
Affinity DataIC50:  18nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM618530(US11759530, Compound Table1.9)
Affinity DataIC50:  30nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50:  47nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM21492(4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...)
Affinity DataIC50:  51nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetActivin receptor type-1B(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50:  129nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM420289(HL-7 | US11759530, Compound Table1.6)
Affinity DataIC50:  130nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails US Patent
TargetCasein kinase I homolog hhp1(Fission yeast)
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  200nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM618551(US11759530, Compound Table1.10)
Affinity DataIC50:  250nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  320nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50:  340nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTGF-beta receptor type-1(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  500nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM420289(HL-7 | US11759530, Compound Table1.6)
Affinity DataIC50:  550nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPurchase
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM21492(4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]quinoline | CH...)
Affinity DataIC50:  740nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPIM2(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50:  3.45E+3nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM618481(US11759530, Compound Table1.4)
Affinity DataIC50:  1.02E+4nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInositol-trisphosphate 3-kinase A(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM618482(US11759530, Compound Table1.5)
Affinity DataIC50:  1.02E+4nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM50298220(2-(4-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50:  1.06E+4nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCasein kinase I isoform delta(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  3.00E+5nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM618551(US11759530, Compound Table1.10)
Affinity DataIC50:  4.50E+6nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  1.20E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPI3a/d(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM618551(US11759530, Compound Table1.10)
Affinity DataIC50:  2.00E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  2.40E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  2.40E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  4.30E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
City of Hope

US Patent
LigandPNGBDBM476219(US10865384, Compound D4476 | US11633415, Compound ...)
Affinity DataIC50:  4.30E+7nMAssay Description:No assay is defined.More data for this Ligand-Target Pair
In DepthDetails US Patent