Found 50 Enz. Inhib. hit(s) with all data for entry = 50000606 
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human HDAC1 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human HDAC2 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC8 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC4 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant HDAC3/NCOR1 co-expressed in insect cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells preincubated for 3 hrs follo...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 co-expressed in baculovirus infected Sf9 insect cells p...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 co-expressed in baculovirus infected Sf9 insect cells p...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells after 1 hr in presence of acetylated l...More data for this Ligand-Target Pair
Affinity DataIC50: 199nMAssay Description:Inhibition of human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells preincubated for 2 hrs followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 1(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 co-expressed in baculovirus infected Sf9 insect cells a...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells preincubated for 2 hrs followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of human full length C-terminal His/FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 cells preincubated for 3 hrs followed by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of human HDAC6 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells preincubated for 2 hrs followed by Fl...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 (395 to 489 residues) co-expressed in baculovirus infec...More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells preincubated for 2 hrs followed by Fl...More data for this Ligand-Target Pair
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells after 1 hr in presence of acetyla...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HDAC6 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) preincubated for 2 hrs followed by Fluor-de-Lys substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) preincubated for 2 hrs followed by Fluor-de-Lys substrate addition measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of HDAC10 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by su...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of full length 6His-tagged HDAC6 (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 17 hrs in presence of F...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of full length 6His-tagged HDAC2 (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 17 hrs in presence of F...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of full length 6His-tagged HDAC8 (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 17 hrs in presence of F...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of C-terminal 6His-tagged HDAC10 (unknown origin) (632 to 669 residues) expressed in baculovirus infected Sf9 insect cells incubated for 1...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of full length 6His-tagged HDAC1 (unknown origin) expressed in baculovirus infected Sf9 insect cells incubated for 17 hrs in presence of F...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length 6His-tagged HDAC3 (unknown origin)/SMRT (395 to 489 residues) (unknown origin) co-expressed in baculovirus infected Sf9 ins...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of HDAC3 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant full length C-terminal GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal His-ABP-tagged HDAC6 expressed in Escherichia coli by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human N-terminal GST-tagged/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf9 insect cells by fl...More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+5nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC5 expressed in baculovirus infected insect cells preincubated for 2 hrs followed by Fluor-d...More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in baculovirus infected insect cells preincubated for 2 h...More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged HDAC7 expressed in baculovirus infected insect cells preincubated for 2 hrs followed by Fluor-d...More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in baculovirus infected insect cells preincubated for 2 h...More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+5nMAssay Description:Inhibition of human recombinant C-terminal His-tagged HDAC5 expressed in baculovirus infected insect cells preincubated for 2 hrs followed by Fluor-d...More data for this Ligand-Target Pair
Affinity DataIC50: >1.80E+5nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged HDAC7 expressed in baculovirus infected insect cells preincubated for 2 hrs followed by Fluor-d...More data for this Ligand-Target Pair
