Found 45 Enz. Inhib. hit(s) with all data for entry = 50010612 TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 129nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 147nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 151nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 165nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 182nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 198nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 244nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 252nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 277nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 313nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 320nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 444nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 474nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 478nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 504nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 606nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.54E+3nMAssay Description:Displacement of [3H]-DAMGO from MOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: >2.00E+3nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University of Catania
Curated by ChEMBL
University of Catania
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-U69,593 from KOR in guinea pig brain membranes incubated for 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]DPDPE from DOR in rat brain membranes incubated for 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
