Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50014451
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50549706(CHEMBL4744083)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576346(CHEMBL4858480)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576347(CHEMBL4849479)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576345(CHEMBL4853796)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576356(CHEMBL4854493)
Affinity DataIC50:  13nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576355(CHEMBL4872767)
Affinity DataIC50:  14nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576357(CHEMBL4850268)
Affinity DataIC50:  18nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576344(CHEMBL4851794)
Affinity DataIC50:  20nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576350(CHEMBL4877327)
Affinity DataIC50:  27nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576351(CHEMBL4866526)
Affinity DataIC50:  29nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576358(CHEMBL4869777)
Affinity DataIC50:  34nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50072084(CHEMBL3407930)
Affinity DataIC50:  34nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576349(CHEMBL4873105)
Affinity DataIC50:  37nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576352(CHEMBL4858343)
Affinity DataIC50:  39nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576354(CHEMBL4846635)
Affinity DataIC50:  62nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576353(CHEMBL4862539)
Affinity DataIC50:  84nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Sumitomo Dainippon Pharma.

Curated by ChEMBL
LigandPNGBDBM50576348(CHEMBL4850797)
Affinity DataIC50:  116nMAssay Description:Inhibition of human liver mitochondrial KMO assessed as reduction in 3-HK metabolite formation using L-kynurenine as substrate preincubated for 5 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed