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Found 3 Enz. Inhib. hit(s) with Target = '1-phosphatidylinositol 3-phosphate 5-kinase' and Ligand = 'BDBM50429615'
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50429615(CHEMBL2334586)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human wild type partial length PIKfyve (F1512 to C2098 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50429615(CHEMBL2334586)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human GST tagged PIKFYVE (1493 to end residues) expressed in baculovirus-infected Sf9 cells using PI(3)P:PS as substrate incubated for ...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Homo sapiens)
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50429615(CHEMBL2334586)
Affinity DataIC50:  14nMAssay Description:Inhibition of PIKFYVE in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed