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Found 2 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50066879'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066879(CHEMBL3401663)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066879(CHEMBL3401663)
Affinity DataIC50:  18nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed