TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by kinase assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human N-terminal His-tagged TEV protease site linked ALK2 Q207D mutant (201 to 499 residues) expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of ALK2 (unknown origin) expressed in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1(Homo sapiens (Human))
Massachusetts Institute Of Technology
Curated by ChEMBL
Massachusetts Institute Of Technology
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 960nMAssay Description:Inhibition of BMP2-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of BMP4-induced BMP receptor in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair