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Found 3 Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50514200'
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50514200(CHEMBL4446378 | US10703733, Comparative Example 1)
Affinity DataKi:  950nMAssay Description:Inhibition of human Biotin-DMRPEIWIAQELRRIGDEFNAYYARR peptide binding to recombinant 10His-tagged human Bcl2 (2 to 211 residues) expressed in Escheri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50514200(CHEMBL4446378 | US10703733, Comparative Example 1)
Affinity DataKi:  950nMAssay Description:Inhibition of recombinant His10-tagged human Bcl-2 (2 to 211 residues) using biotinylated Bim BH3 peptide as substrate incubated for 60 mins by TR-FR...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50514200(CHEMBL4446378 | US10703733, Comparative Example 1)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of recombinant C-terminal His10x-tagged human Bcl-2 (2 to 211 residues) expressed in Escherichia coli cells interaction with biotinylated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed