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Found 3 Enz. Inhib. hit(s) with Target = 'B2 bradykinin receptor' and Ligand = 'BDBM50293884'
TargetB2 bradykinin receptor(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50293884(8-[3-chloro-5-(thiazol-2-ylsulfanyl)-pyridin-4-ylm...)
Affinity DataIC50:  29nMAssay Description:Antagonist activity at B2 receptor in human HF15 cells assessed as inhibition of bradykinin-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50293884(8-[3-chloro-5-(thiazol-2-ylsulfanyl)-pyridin-4-ylm...)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]bradykinin from human recombinant B2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB2 bradykinin receptor(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50293884(8-[3-chloro-5-(thiazol-2-ylsulfanyl)-pyridin-4-ylm...)
Affinity DataIC50:  470nMAssay Description:Displacement of [3H]bradykinin from wild-type B2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed