Found 14 Enz. Inhib. hit(s) with Target = 'Gastrin/cholecystokinin type B receptor' and Ligand = 'BDBM50449787' TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.355nMAssay Description:Inhibition by displacing [3H]CCK-8S against human Cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Compound was tested for the affinity against Cholecystokinin type B receptor on guinea pig cortex.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 0.980nMAssay Description:The compound was evaluated for the inhibition of binding of [3H]-PD 140376 to Cholecystokinin type B receptor in guinea pig cortex.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type B receptor of guinea pigMore data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Compound was tested for binding affinity against rat brain Cholecystokinin type B receptor expressed in CHO cells.More data for this Ligand-Target Pair
Affinity DataKi: 269nMAssay Description:Inhibition by displacing [3H]CCK-8S against Cholecystokinin type B receptor of rat pancreatic membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Glaxo Wellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.138nMAssay Description:In vitro displacement of [125I]BH-CCK-8 from cDNA of human Cholecystokinin type B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Half-maximal inhibition of specific binding of [125I]bolton hunter CCK-8 to mouse cerebral cortex Cholecystokinin type B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of binding of [125I]- Bolton-Hunter labeled CCK-8 to CCK-B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of [125I]-CCK-8 to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Compound measured for half-maximal inhibition of specific binding of [125I]-Bolton Hunter CCK-26-33 to CCK-B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against radioligand [125I]Bolton-Hunter labeled CCK-8 to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of inositol phosphate production induced by Cholecystokinin type B receptor (0.5 nM)More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortexMore data for this Ligand-Target Pair
