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Found 3 Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM35554'
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Irbm, Mrl Rome

LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50:  9nMpH: 7.5 T: 2°CAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50:  35nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 2b (isolate HC-J8) (HCV...)
Irbm, Mrl Rome

LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50: >1.00E+4nMAssay Description:Primer-dependent assays were performed using the homopolymeric template/primer. Compounds, polymerase and template RNA were incubated at RT for 25 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed