TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 0.00950nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 minsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]DAMGO from Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]endomorphin-2 from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.33nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.33nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.35nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 2.06nMAssay Description:Binding affinity towards mu receptor in rat brain using [3H]DAMGOMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DAMGO from human recombinant MOR expressed in CHO cell membranes incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DAMGO from rat cortex mu opioid receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Inhibition of [3H]-naloxone binding to rat brain homogenate Opioid receptor muMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-endomorphin-2 from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 8.23nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 9.53nMAssay Description:Displacement of [3H]-DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 9.56nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 9.60nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-DAMGO from Wistar rat mu opioid receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.690nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from MOR in rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.990nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.46nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 4.70nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 6.88nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig intestine assessed as inhibition of electrically evoked myenteric plexus longitudinal mu...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 6.90nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 7.70nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 9.22nMAssay Description:Inhibition of Opioid receptor mu 1 of guinea pig ileumMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 9.30nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 9.67nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 13.7nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 14nMAssay Description:Agonist activity at mu opioid receptor by guinea pig ileum assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 14.7nMAssay Description:In vitro inhibitory concentration against Opioid receptor mu 1 was measured using guinea pig ileum assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 15nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Clinical Research Institute of Montreal
Curated by PDSP Ki Database
Affinity DataIC50: 15nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair