Found 9 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM50026612' 
Affinity DataKi: 8nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:H1-antihistamine activity on guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human N-terminal GST-tagged PDGFRbeta cytoplasmic domain (557 to 1106 residues) expressed in baculovirus expression system preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of N-terminal GST-fused human PDGFRbeta cytoplasmic domain (557 to 1106 (end) residues) expressed in baculovirus expression system using F...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair
