Found 3 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50201028' TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceuticals
US Patent
Janssen Pharmaceuticals
US Patent
Affinity DataIC50: 8.01nMAssay Description:After thawing on the day of the assay, the membrane suspension was diluted further with 20 mM HEPES/0.1 mM KCl/pH 7.2.The incubation mixture of 200 &...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceuticals
US Patent
Janssen Pharmaceuticals
US Patent
Affinity DataIC50: 1.35E+5nMAssay Description:Binding was terminated by filtration of the incubated membrane preparations using Filtermat B (Pharmacia, Uppsala Sweden) and a Micro Cell Harvester ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceuticals
US Patent
Janssen Pharmaceuticals
US Patent
Affinity DataIC50: 1.35E+5nMAssay Description:Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
