Found 5 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 6' and Ligand = 'BDBM178103' 
Affinity DataKi: 0.800nM IC50: 4nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 4nMAssay Description:Inhibition of human PRMT6 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation prox...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT6 (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of PRMT6 (unknown origin) using biotinylated histone H4 (1 to 24 residues) as substrate in presence of [3H]SAM by scintillation proximity ...More data for this Ligand-Target Pair
Affinity DataKd: 6nMpH: 8.5Assay Description:Isothermal titration calorimetry (ITC) was performed at 25 °C in a Nano ITC instrument (TA Instruments, USA). The cell was loaded with 25 μM PRM...More data for this Ligand-Target Pair
