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Found 4 Enz. Inhib. hit(s) with Target = 'Ribonucleoside-diphosphate reductase large subunit/subunit M2' and Ligand = 'BDBM601197'
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601197(N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...)
Affinity DataIC50:  50nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601197(N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...)
Affinity DataIC50:  60nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601197(N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...)
Affinity DataIC50:  70nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM601197(N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...)
Affinity DataIC50:  80nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent