Found 3 Enz. Inhib. hit(s) with Target = 'Stimulator of interferon genes protein' and Ligand = 'BDBM50604466' TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 0.0623nMAssay Description:Binding affinity to recombinant human His-tagged STING by measuring fluorescent signals in the presence of d2 labelled STING wild type ligand by HTRF...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Activation of STING mediated immune response in human THP-1 cells assessed as induction of IFNbeta secretion measured after 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataEC50: 0.354nMAssay Description:Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hr...More data for this Ligand-Target Pair
