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Found
1
Enz. Inhib. hit(s) with Target = 'hek293 luciferase' and Ligand = 'BDBM578687'
Target
hek293 luciferase
(Human immunodeficiency virus type 1 group M subtyp...)
Medimmune
US Patent
Ligand
BDBM578687
(3-[5'-(difluoromethoxy)- 5-fluoro[3,3'-bipyridin]-...)
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Affinity Data
EC50: 14nM
Assay Description:
Purpose of the AssayThe purpose of this assay is to identify small molecule inhibitors of Keap1, preventing Keap1 binding to Nrf2, and thus activatin...
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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