Compile Data Set for Download or QSAR
maximum 50k data
Found 14 of ki for UniProtKB: P17787
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM397477(US9993465, Sazetidine-A)
Affinity DataKi:  0.0870nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM50166908(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca...)
Affinity DataKi:  0.480nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM397483(US9993465, (S)-17)
Affinity DataKi:  5.30nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]epibatidine from alpha2beta2 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM397485(US9993465, (S)-21)
Affinity DataKi:  8.60nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM397484(US9993465, (S)-22)
Affinity DataKi:  8.70nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM50004108((+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3...)
Affinity DataKi:  12nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM397482(US9993465, (S)-27)
Affinity DataKi:  13nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM397478(US9993465, (R)-15 | US9993465, (S)-15)
Affinity DataKi:  16nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM397480(US9993465, (R)-16 | US9993465, (S)-16)
Affinity DataKi:  130nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM397478(US9993465, (R)-15 | US9993465, (S)-15)
Affinity DataKi:  970nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM50400739(CHEMBL2203550)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha2beta2 nAChR after 4 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM397480(US9993465, (R)-16 | US9993465, (S)-16)
Affinity DataKi:  2.20E+4nMAssay Description:Briefly, cultured cells at >80% confluence were removed from their flasks (80 cm2) with a disposable cell scraper and placed in 10 mL of 50 mM Tris.H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Homo sapiens (Human))
Georgetown University

US Patent
LigandPNGBDBM50162985(2-Methyl-4-[5-((S)-1-methyl-pyrrolidin-2-ylmethoxy...)
Affinity DataKi:  6.10E+4nMAssay Description:Binding affinity against nicotinic acetylcholine receptor subtype alpha2-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed