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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515186(CHEMBL4462550)

IC50: 0.350nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515196(CHEMBL4454232)

IC50: 0.370nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515192(CHEMBL4556075)

IC50: 0.460nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515195(CHEMBL4443845)

IC50: 0.550nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515185(CHEMBL4585225)

IC50: 0.570nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515189(CHEMBL4463134)

IC50: 0.650nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515188(CHEMBL4531333)

IC50: 0.920nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515187(CHEMBL425006)

IC50: 0.930nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515190(CHEMBL4440025)

IC50: 0.950nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515194(CHEMBL4559471)

IC50: 1.10nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515193(CHEMBL4518954)

IC50: 1.40nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50515191(CHEMBL371789)

IC50: 1.70nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50329475((S)-N-(1-(3-(4-(3-aminopropylamino)butylamino)prop...)

IC50: 2.20nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50001695(CHEMBL3238085)

IC50: 2.30nMAssay Description:Inhibition of alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-evoked current by voltag...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50329473((S)-N-(1-(3-(4-(3-aminopropylamino)butylamino)prop...)

IC50: 2.60nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50329474((S)-N-(1-(3-(4-(3-aminopropylamino)butylamino)prop...)

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50329476((S)-N-(1-(3-(4-(3-aminopropylamino)butylamino)prop...)

IC50: 2.80nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50094298(CHEMBL16117 | N-[(S)-1-{3-[4-(3-Amino-propylamino)...)

IC50: 7.70nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced channel activatio...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50597657(CHEMBL5174461)

IC50: 65nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in SH-SY5Y cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50490639(CHEMBL2332278)

IC50: 80nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50445327(CHEMBL3104240)

IC50: 97nMAssay Description:Inhibition of alpha3beta4 nAChR (unknown origin) expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50001697(CHEMBL3238027)

IC50: 97nMAssay Description:Antagonist activity at alpha3beta4 nAChR (unknown origin)More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50441363(CHEMBL2332280)

IC50: 100nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50369323(MECAMYLAMINE)

IC50: 100nMAssay Description:Inhibitory activity against nicotinic acetylcholine receptor alpha3-beta4More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50567433(CHEMBL4869892)

IC50: 179nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-ele...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50490640(3-Benzhydrylquinuclidine | CHEMBL2332279)

IC50: 200nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of calcium influx by calcium-4 based FLIPR analysisMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50597656(CHEMBL5209526)

IC50: 347nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in SH-SY5Y cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50441363(CHEMBL2332280)

IC50: 380nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50441363(CHEMBL2332280)

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50490640(3-Benzhydrylquinuclidine | CHEMBL2332279)

IC50: 398nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50508934(CHEMBL4463817)

IC50: 400nMAssay Description:Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50490640(3-Benzhydrylquinuclidine | CHEMBL2332279)

IC50: 400nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50587088(CHEMBL5082749)

IC50: 501nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in SH-SY5Y cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50445325(CHEMBL3104238)

IC50: 518nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophy...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50490639(CHEMBL2332278)

IC50: 600nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50490639(CHEMBL2332278)

IC50: 603nMAssay Description:Non-competitive antagonist activity at human alpha3beta4 nAChR expressed in CHO cells assessed as inhibition of nicotine-induced calcium influx incub...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50445323(CHEMBL3104236)

IC50: 755nMAssay Description:Antagonist activity at human alpha3beta4 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophy...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50001727(CHEMBL3238025)

IC50: 755nMAssay Description:Inhibition of human alpha3beta4 nAChR expressed in Xenopus laevis oocytes by two-electrode voltage clamp techniqueMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50341207((S,S)-2-(3'-Chlorophenyl)-4-ethyl-3,5,5-trimethylm...)

IC50: 790nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50339933(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)

IC50: 800nMAssay Description:Inhibition of alpha3beta4 nAChRMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50508933(CHEMBL4461511)

IC50: 960nMAssay Description:Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50341208((S,S)-2-(3'-Chlorophenyl)-3,5,5-trimethyl-4-propyl...)

IC50: 980nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50451971(CHEMBL330867)

IC50: 1.20E+3nMAssay Description:Effect on alpha3-beta4 neuronal nicotinic acetylcholine receptor-stimulated adrenal catecholamine secretionMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50322520((2S,3S)-2-Biphenyl-4-yl-3,5,5-trimethylmorpholin-2...)

IC50: 1.30E+3nMAssay Description:Antagonist activity at alpha3beta4 nicotinic receptor in human SH-SY5Y cells assessed as inhibition varbamylcholine-induced radiolabeled Rb+ influx a...More data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50451974(CHEMBL340342)

IC50: 1.30E+3nMAssay Description:Effect on alpha3-beta4 neuronal nicotinic acetylcholine receptor-stimulated adrenal catecholamine secretionMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50149051(2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-benzoic ac...)

IC50: 1.30E+3nMAssay Description:Effect on alpha3-beta4 neuronal nicotinic acetylcholine receptor-stimulated adrenal catecholamine secretionMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50451972(CHEMBL125960)

IC50: 1.30E+3nMAssay Description:Effect on alpha3-beta4 neuronal nicotinic acetylcholine receptor-stimulated adrenal catecholamine secretionMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50597655(CHEMBL5185118)

IC50: 1.35E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in SH-SY5Y cells assessed as inhibition of calcium flux by FLIPR assayMore data for this Ligand-Target Pair

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Neuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
University Of Nottingham

Curated by ChEMBL

BDBM50322528((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...)

IC50: 1.40E+3nMAssay Description:Antagonist activity at human alpha3beta4 nAChR in HEK293 cells assessed as inhibition of carbamylcholine-induced radiolabeled Rb ion effluxMore data for this Ligand-Target Pair