Compile Data Set for Download or QSAR
maximum 50k data
Found 432 of ic50 for UniProtKB: P08909
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)
Affinity DataIC50:  0.0820nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50010041(CHEMBL84087 | {1-[3-(1,1-Dioxo-1H-1lambda*6*-napht...)
Affinity DataIC50:  0.100nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50010048(2-[3-(4-Phenyl-piperidin-1-yl)-propyl]-2H-naphtho[...)
Affinity DataIC50:  0.200nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001991(1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50010049(4-{4-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]is...)
Affinity DataIC50:  0.300nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002008(1-(2-{4-[1-(4-Fluoro-phenyl)-5-methyl-1H-indol-3-y...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001990(5-Chloro-1-(4-fluoro-phenyl)-3-(4-methyl-piperazin...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [3H]ketanserin binding to dopamine 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001786(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
Affinity DataIC50:  0.390nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001786(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
Affinity DataIC50:  0.390nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  0.400nMAssay Description:Compound was tested for the displacement of [3H]ketanserin from serotonin 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  0.400nMAssay Description:Compound was tested for the displacement of [3H]ketanserin from serotonin 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50010038(2-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pr...)
Affinity DataIC50:  0.400nMAssay Description:Binding constant against dopamine receptor D2 (in vivo)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007692(8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor measured using radioligand ([3H]spiperone) binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001786(1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002001(1-(2-{4-[5-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007567(1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-y...)
Affinity DataIC50:  0.480nMAssay Description:Ability to inhibit binding of [3H]KET to 5-hydroxytryptamine 2 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50007568(1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-...)
Affinity DataIC50:  0.480nMAssay Description:Ability to inhibit binding of [3H]KET to 5-hydroxytryptamine 2 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50010044(2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-...)
Affinity DataIC50:  0.5nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002015(5-Chloro-1-(4-fluoro-phenyl)-3-(1-methyl-1,2,3,6-t...)
Affinity DataIC50:  0.530nMAssay Description:Inhibition of [3H]ketanserin binding to dopamine 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50025124(3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-...)
Affinity DataIC50:  0.562nMAssay Description:Evaluated for binding activity against [3H]ketanserin as radioligand for 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM22872(1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...)
Affinity DataIC50:  0.570nMAssay Description:Ability to inhibit binding of [3H]KET to 5-hydroxytryptamine 2 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001797(1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-y...)
Affinity DataIC50:  0.590nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001778((Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3...)
Affinity DataIC50:  0.720nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001790(1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  0.730nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001885((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)
Affinity DataIC50:  0.760nMAssay Description:Inhibition of [3H]ketanserin binding to dopamine 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001796(1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-y...)
Affinity DataIC50:  0.820nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50230290(CHEMBL344273 | MDL-28161)
Affinity DataIC50:  0.900nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50368656(CHEMBL1204307 | CHEMBL1744111)
Affinity DataIC50:  0.950nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50368656(CHEMBL1204307 | CHEMBL1744111)
Affinity DataIC50:  0.950nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002014(1-(2-{4-[1-(4-Fluoro-phenyl)-5-methoxy-1H-indol-3-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50010040(2-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl...)
Affinity DataIC50:  1nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001997(1-(2-{4-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002004(1-(3-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50229423(CHEMBL82229)
Affinity DataIC50:  1nMAssay Description:The concentration required to inhibit [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor in rat brain membranes (in vitro)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50368675(CHEMBL1744113)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50368675(CHEMBL1744113)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001776(1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-y...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001784(3-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002000(1-(4-Fluoro-phenyl)-3-{1-[2-(2-oxo-imidazolidin-1-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002013(1-(2-{4-[5-Bromo-1-(4-fluoro-phenyl)-1H-indol-3-yl...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001789(1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50004813(8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phe...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]-spiperone from rat frontal cortex 5-HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001772(1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor from rat cortical membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001994(2-{4-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-ind...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of [3H]ketanserin binding to dopamine 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001782((Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50368662(CHEMBL1744107)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50002010(1-(5-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50368668(CHEMBL1788128)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50001811(1-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-...)
Affinity DataIC50:  1.5nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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