Compile Data Set for Download or QSAR
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Found 3 of ec50 for monomerid = 313219
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313219(US10166249, Example 449)
Affinity DataEC50:  55nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine-1-phosphate lyase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313219(US10166249, Example 449)
Affinity DataEC50:  55nMAssay Description:hS1P1/CHO cells were plated into BD Amine 384-well plates the day before the assay. On the day of the assay, growth medium was removed and replaced w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM313219(US10166249, Example 449)
Affinity DataEC50: >625nMAssay Description:Compounds were loaded in a 384 Falcon v-bottom plate (0.5 l/well in a 11 point, 3-fold dilution). Membranes prepared from S1P1/CHO cells or EDG3-Gal5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent