Affinity DataEC50: 0.324nMAssay Description:Inhibition of forskolin stimulated cAMP accumulation in CHO cells stably expressing the human OP4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.513nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of calcium mobilization by Fluo-4 AM dye based analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 0.780nMAssay Description:Agonist activity at human NOP receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.12nMAssay Description:Efficacy for human ORL1 receptor expressing HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 7.82nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 8.30nMAssay Description:Agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing Gbeta1-RGFP protein assessed as induction of G protein acti...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at NOP (unknown origin) expressed in HEK293 cell membranes co-expressing beta-arrestin2-RGFP protein assessed as induction of beta-a...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at NOR in mouse Neuro-2a cells assessed as stimulation of ERK phopshorylation after 30 mins post dose by Alphascreen Surefire assayMore data for this Ligand-Target Pair
Affinity DataEC50: 51nMAssay Description:Activity at Wistar rat NOP receptor assessed as inhibition of low-frequency electrically-stimulated vas deferens contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 398nMAssay Description:Activity against LFES-evoked contraction of Wistar rat vas deferens in presence of naloxoneMore data for this Ligand-Target Pair
Affinity DataEC50: 575nMAssay Description:Activity against LFES-evoked contraction of Wistar rat vas deferensMore data for this Ligand-Target Pair