Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ec50 for monomerid = 50323528
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50323528(2-(4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisox...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human full length FXR transfected in HEK293 cells coexpressing pTRexDest/pGL2promotor assessed as luciferase activity by direct r...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50323528(2-(4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisox...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human GST-fused FXR LBD assessed as cofactor peptide interaction with receptor ligand binding domain by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Phenex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50323528(2-(4-(((6-((3-(2,6-dichlorophenyl)-5-isopropylisox...)
Affinity DataEC50:  214nMAssay Description:Agonist activity at human GST-fused FXR LBD expressed in HEK293 cells coexpressing GAL4-DNA bindig domain and pFRluc by mammalian one-hybrid assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed