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Found 3 of ec50 for monomerid = 50447286
TargetGlucokinase regulatory protein(Rattus norvegicus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)
Affinity DataEC50:  3.64E+3nMAssay Description:Inhibition of GKRP-GK interaction in rat primary hepatocytes assessed as translocation of GK from nucleus to cytoplasm preincubated for 20 mins follo...More data for this Ligand-Target Pair
TargetHexokinase-4(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)
Affinity DataEC50: >1.25E+4nMAssay Description:Induction of GK translocation from nucleus to cytoplasm of mouse hepatocytes preincubated for 20 mins followed by glucose challenge measured after 40...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50447286(CHEMBL3113992)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of human glucokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed