Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:The Ki values were determined as described in the literature [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. Enzyme I...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.75E+3nMAssay Description:Carbonic anhydrase (CA) activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al...More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 hydratase activity by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.25E+3nMAssay Description:Inhibition of CO2-hydratase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.35E+3nMAssay Description:Carbonic anhydrase (CA) activity was assayed by following the hydration of CO2 according to the method described by Wilbur and Anderson [Wilbur et al...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:The Ki values were determined as described in the literature [Landolfi et al., J. Pharmacol. Toxicol. Methods, 38:169-172; Bülbül et al., J. Enzyme I...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMpH: 7.4Assay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
TargetEndochitinase A1(Neosartorya fumigata (Aspergillus fumigatus))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Aspergillus fumigatus ChiA1 expressed in Pichia pastoris after 70 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+6nM IC50: 1.24E+6nMAssay Description:The inhibitory effects of six sulfonamide derivatives was examined against the purified enzyme hPON1 and were tested in a triplicate experiment in fi...More data for this Ligand-Target Pair