Compile Data Set for Download or QSAR
maximum 50k data
Found 7 of ic50 for monomerid = 14948
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50: <1nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck [245-498](Homo sapiens (Human))
Amgen

LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50: <1nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50:  3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50:  3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research

Curated by ChEMBL
LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of Yes1 (unknown origin) assessed as kinase-dependent enzymatic production of ADP from ATP using coupled luminescence-based reaction by AD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Frederick National Laboratory For Cancer Research

Curated by ChEMBL
LigandPNGBDBM14948(4-Methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyrid...)
Affinity DataIC50:  22nMAssay Description:Inhibition of Yes1 (unknown origin) by [gamma-33P]-ATP radiolabeled enzyme activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed