Found 3 of ic50 for monomerid = 18428 TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences
Curated by ChEMBL
National Center For Advancing Translation Sciences
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences
Curated by ChEMBL
National Center For Advancing Translation Sciences
Curated by ChEMBL
Affinity DataKi: 21nM ΔG°: -43.2kJ/mole IC50: 31nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center For Advancing Translation Sciences
Curated by ChEMBL
National Center For Advancing Translation Sciences
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
