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Found 3 of ic50 for monomerid = 228117
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228117((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228117((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  4.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228117((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  18.4nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent