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Found 3 of ic50 for monomerid = 259517
TargetPoly [ADP-ribose] polymerase tankyrase-2 [946-1162](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM259517(US9505749, 28)
Affinity DataIC50:  0.303nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-1 [1091-1325](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM259517(US9505749, 28)
Affinity DataIC50:  0.531nMAssay Description:The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM259517(US9505749, 28)
Affinity DataIC50:  1.76E+3nMAssay Description:PARP1 biochemical assay was purchased as a kit from Trevigen (cat.#4676-096-K) and used per manufacturers recommendations.PARP2 biochemical assay was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent